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KMID : 1025520110530010075
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Journal of Animal Science and Technology
2011 Volume.53 No. 1 p.75 ~ p.81
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Effects of Fermented Turmeric Extracts on the Obesity in Rats Fed a High-Fat Diet
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Yang Cheul-Young
Cho Mi-Jin
Lee Chi-Ho
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Abstract
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This study was designed to investigate the effects of fermented turmeric extract on body weight, abdominal fat mass and biochemical markers related to obesity in rats fed high fat diet. Turmeric and brown sugar was equally mixed and fermented for one year. Wistar rats(weighing about 125g(15 rats)) were divided into three groups: high fat diet(20.9%) and brown sugar 7.2% (HFD), turmeric powder in replace of corn starch 12.8%, brown sugar 7.2% (TP), fermented turmeric powder 20%(FTP) for four weeks. The final body weight was about 425g. The retroperitoneal fat weights in TP group showed the tendency to decrease regardless of feed intake in the rats. Serum levels of total cholesterol and LDL-cholesterol in the FTP group showed the lowering tendency than those of the HFD group(p<0.05). Serum levels of leptin, adiponectin and aspartate aminotransferase(AST) in the FTP group was significantly(p<0.05) lower than that of the HFD group, and serum level of tumor necrosis factor-α(TNF-α) in all the groups were similar. These results suggest that fermented turmeric extract might be effective to prevent obesity in rats fed high fat diet.
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KEYWORD
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Fermented turmeric, Rats, Obesity, Leptin, AST
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